Product Identification

Product Name

Methyl methanesulfonate

Synonyms

as-Dimethyl sulfite
as-Dimethyl sulphite
Methyl mesylate
Methyl methanesulfonic acid
Methylmethane sulfonate
Methylmethanesulphonate

CAS

66-27-3

Formula

C2H6O3S

Molecular Weight

110.12

EINECS

200-625-0

RTECS

PB2625000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

12,6170

Beilstein/Gmelin

1098586

Beilstein Reference

4-04-00-00011

Physical and Chemical Properties

Appearance

Colorless to amber liquid.

Solubility in water

Very soluble

Melting Point

20

Boiling Point

203

Vapor Pressure

0.42 (25 C)

Density

1.3206 g/cm3 (0 C)

Partition Coefficient

-.57

Heat Of Vaporization

42.0 kJ/mol

Usage

Research chemical.

Refractive Index

1.41248 (16.2 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See inhalation.

Inhalation

Symptoms of exposure to this compound may include irritation of the eyes, skin, mucous membranes, nose and respiratory tract. It can cause dermatitis and nausea. Large doses ingested over nearly a year produced gastrointestinal and hepatic toxic effects.

Skin

See inhalation.

Eyes

See inhalation

Hazards

Contact with metals may evolve flammable hydrogen gas.

UN (DOT)

2922

Exposure Controls/Personal Protection

Personal Protection

If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Fire Fighting Measures

Flash Point

104

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong acids - strong bases.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2922

Hazard Class

8

Packing Group

I; II; III