Product Identification

Product Name

3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone

Synonyms

3,3-bis(4-Hydoroxyphenyl)-1(3H)-isobenzofuranone
3,3-bis(4-Hydroxyphenyl)-2-benzofuran-1-one

CAS

77-09-8

Formula

C20H14O4

Molecular Weight

318.33

EINECS

201-004-7

RTECS

SM8380000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Human Data

Merck

12,7392

Beilstein/Gmelin

284423

Beilstein Reference

5-18-04-00188

Physical and Chemical Properties

Appearance

White or yellowish-white crystals, odorless.

Solubility in water

0.092 g/L (20 C)

Melting Point

258 - 262

Density

1.3 g/cm3

pKa/pKb

9.7 (pKa)

Partition Coefficient

2.41

Usage

Acid base indicator, laboratory reagent. Used medicinally as a cathartic.

Vapor Density

11

Refractive Index

1.57 (7.9 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Get medical aid. Wash clothing before reuse. Flush skin with plenty of soap and water.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause irritation of the digestive tract. Expected to be a low ingestion hazard.

EC Risk Phrase

R 40

EC Safety Phrase

S 22 36/37

UN (DOT)

1993

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Possible cancer hazard based on tests with laboratory animals. Prolonged or repeated exposure may cause adverse reproductive effects. May cause kidney injury.

Poison Class

3

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

UN Number

1993

HS Code

2932 29 10