Product Identification

Product Name

2-(5-Methoxy-3-methyl-1-pyrazinyl)-4-methoxy-6-methyl-pyrimidine

Synonyms

1-(4'-Methoxy-6'-methyl-2'-pyrimidinyl)-3-methyl-5-methoxypyrazole
1-(4-Methyl-6-methoxy-2-pyrimidinyl)-3-methyl-5-methoxypyrazole
2-(3-Methoxy-5-methylpyrazol-2-yl)-4-methoxy-6-methylpyrimidine
4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine
Mepirizole

CAS

18694-40-1

Formula

C11H14N4O2

Molecular Weight

234.26

EINECS

242-507-1

RTECS

UV9290000

RTECS Class

Drug

Merck

12,3659

Beilstein/Gmelin

751084

Beilstein Reference

5-25-18-00012

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

90 - 92

Boiling Point

444

Vapor Pressure

4E-8 (25 C)

pKa/pKb

13.35 (pKb)

Heat Of Vaporization

70.2 kJ/mol

Usage

A pyrimidinyl pyrazole with antipyretic, analgesic, and anti-inflammatory activity.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2 - 8 C.

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22 36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin.

Fire Fighting Measures

Flash Point

222

Fire Fighting

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.