Product Identification

Product Name

Diisobutylaluminium hydride

Synonyms

Bis(2-methylpropyl)alumane
Bis(isobutyl)aluminum hydride
Diisobutylaluminium hydride
Diisobutylaluminum
Diisobutylhydroaluminum
Hydrodiisobutylaluminum

CAS

1191-15-7

Formula

C8H19Al

Molecular Weight

142.25

EINECS

214-729-9

RTECS

BD0710000

RTECS Class

Other

Beilstein/Gmelin

4123663

Beilstein Reference

4-04-00-04400

Physical and Chemical Properties

Appearance

Colorless liquid.

Melting Point

-80

Boiling Point

95.5 - 96.5 (0.2 torr)

Density

0.798 g/cm3 (20 C)

Heat Of Vaporization

Heat Of Combustion

-6412 kJ/mol

Usage

Reducing agent in pharmaceuticals.

First Aid Measures

Ingestion

Mucosal if no respiratory compromise is present, dilute immediately with milk or water; no more than 8 ounces in adults and 4 ounces in children. Gastric ipecac contraindicated. Consider insertion of a small, flexible nasogastric or orogastric tube to suction gastric contents after recent large ingestions; the risk of further mucosal injury must be weighed against potential benefits.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothes. Irrigate exposed skin with copious amounts of water for at least 15 minutes or longer, depending on concentration, amount and duration of exposure to the chemical. A physician may need to examine the area if irritation or pain persist.

Eyes

Home irrigation - exposed eyes should be irrigated with copious amounts of water for at least 30 minutes. An examination should always be performed. Ophthalmologic consultation should be obtained. Medical facility: irrigate with sterile 0.9% Saline for at least an hour or until the cul-de-sacs are free of particulate matter and returned to neutrality (confirm with pH paper).

Handling and Storage

Storage

Aluminum alkyls. In undiluted condition. Must be kept under inert gas like nitrogen or argon, and all possibility of contact with water must be avoided. Solution containing not more than 20% of these compd in non-reactive solvents, however, can be handled without risk of spontaneous ignition. Aluminum alkyls in general, toxic materials or that can decompose into toxic components should be stored in cool ventilated place, out of sun, away from fire hazard. Substance must be periodically inspected and monitored. Incompatible materials should be isolated.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Stridor, dyspnea, upper airway injury, and pulmonary edema, especially following inhalation of vaporized caustics, may occur.

Skin

Severe skin irritation and/or burns may occur.

Eyes

See Skin.

Ingestion

Burns of the esophagus and less commonly the stomach may occur after caustic ingestion; the absence of oral mucosal injury does not reliably exclude esophageal burns. Patients with stridor, drooling or vomiting are more likely to have esophageal burns.

Hazards

May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. May react vigorously or explosively on contact with water. May decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished.

EC Risk Phrase

R 11 14/15 17 20 35

EC Safety Phrase

S 16 25 36/37/39 43 45

UN (DOT)

3051

Exposure Controls/Personal Protection

Personal Protection

Protective clothing and high standard of training in necessary precautionary measures are essential for handling of materials.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Headache, myalgias, weakness, and paresthesias in both feet have been reported. Aluminum in drinking water has been linked to central nervous system birth defects. Some aluminum compounds have proven teratogenic in laboratory animals; however, overall, aluminum is not considered teratogenic.

Exposure limit(s)

OSHA: PEL (8 h TWA): 15 mg/m3.

Poison Class

1

Fire Fighting Measures

Flash Point

4

Fire Fighting

Do not use water, foam or halogenated extinguishing agents.

Fire Potential

The undiluted material ignites in air unless diluted to below 25% concentration. Certain polymerization catalysts, such as aluminum alkyls, react and burn violently on contact with water. Aluminum alkyls aluminum alkyls are organic aluminum compounds that are highly reactive and dangerous because of spontaneous burning in air. Aluminum alkyls ignites spontaneously in air.

Accidental Release Measures

Small spills/leaks

Use a fully encapsulating, vapor protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources and prevent all contact with spilled material. Stop leak if you can do it without risk. Cover with DRY earth, DRY sand, or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean non-sparking tools to collect material and place it into loosley covered plastic containers for later disposal. This is a generic DOT guideline. EXCEPTION: For Dithionite (Hydrosulfite/Hydrosulphite) spills, UN1384, UN1923 and UN1929, dissolve with 5 parts water and collect for proper disposal.

Stability and Reactivity

Incompatibilities

Extremely reactive with air, moisture, and compounds containing active hydrogen alkyl aluminum compounds

Stability

Less sensitive to oxidation in air than trialkylaluminums aluminum alkyls.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3051

Hazard Class

4.2

Packing Group

I