Product Identification

Product Name

N,N'-Diphenylhydrazine

Synonyms

1,2-Di(phenyl)hydrazine
Diphenylhydrazine
Hydrazobenzene
N,N'-Bianiline

CAS

122-66-7

Formula

C12H12N2

Molecular Weight

184.26

EINECS

204-563-5

RTECS

MW2625000

RTECS Class

Tumorigen; Mutagen

Beilstein/Gmelin

639793

Beilstein Reference

4-15-00-00056

EC Index Number

007-021-00-4

EC Class

Carcinogenic Category 2; Harmful; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Orange powder or a bright orange crystalline solid.

Solubility in water

1 g/L

Melting Point

123

Boiling Point

309

Vapor Pressure

0.07 (25 C)

Density

1.158 g/cm3 (16 C)

Partition Coefficient

2.94

Heat Of Vaporization

46.6 kJ/mol

Heat Of Combustion

-6695 kJ/mol

Usage

Chemical intermed for benzidine, an intermed for dyes, in synthesis of phenylbutazone (antiarthritic drug).

Odor threshold

1-10 ppm

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Hazards

Contact with metals may evolve flammable hydrogen gas.

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Animal studies have reported the development of tumors.

Poison Class

1*

Fire Fighting Measures

Flash Point

88

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Upper exp. limit

5.5

Lower exp. limit

.7

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III