Pemoline(2152-34-3)
Product Identification
Product Name
Pemoline
Synonyms
2-Amino-5-phenyl-4(5h)-oxazolone
Azoksodon
Azoxodone
Centramin
Constimol
Cs 293
CAS
2152-34-3
Formula
C9H8N2O2
Molecular Weight
176.17
EINECS
218-438-8
RTECS
RQ2975000
RTECS Class
Drug; Reproductive Effector; Human Data
Merck
12,7206
Beilstein/Gmelin
151559
Beilstein Reference
4-27-00-05622
First Aid Measures
Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Handling and Storage
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Hazards Identification
Inhalation
Tachypnea is common. Pulmonary hypertension has been associated with chronic use or abuse which may result from contaminants. Pulmonary edema and ards are unusual complications of severe exposure.
Skin
The skin is usually flushed and diaphoretic.
Ingestion
Vomiting, diarrhea, cramps, anorexia and gastrointestinal hemorrhage may occur.
Exposure Controls/Personal Protection
Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Exposure Effects
Severe elevated body temperature may develop. Elevated blood pressure and rapid heart rate are common. Agitation, confusion, paranoia, delirium, hallucinations, restlessness, hyperactivity, talkativeness, irritability, insomnia, and headache are common. Chorea, dystonia, fasciculations, muscle rigidity, tics, and tremors may develop. Seizures and coma may occur with severe intoxication. Other neurological effects have included stroke and cerebral vasculitis. Serotonin syndrome has occurred.
Fire Fighting Measures
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.