Product Identification

Product Name

1-Amino-4-carboxybenzene

Synonyms

1-Amino-4-carboxybenzene
p-Aminobenzoic acid

CAS

150-13-0

Formula

C7H7NO2

Molecular Weight

137.13999999999999

EINECS

205-753-0

RTECS

DG1400000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector

Merck

13,422

Beilstein/Gmelin

471605

Beilstein Reference

4-14-00-01126

Physical and Chemical Properties

Appearance

White to tan crystalline powder.

Solubility in water

Very soluble

Melting Point

188

Boiling Point

340

Vapor Pressure

3E-5 (25 C)

Density

1.45 g/cm3 (20 C)

pKa/pKb

4.65 (pKa)

Partition Coefficient

.01

Heat Of Vaporization

61.6 kJ/mol

Usage

Manufacture of various esters (local anesthetics), folic acid, and azo dyes,. Used in laboratories as sulfonamide antagonist.

Refractive Index

1.5795

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Overexposure may cause methemoglobinemia.

EC Risk Phrase

R 36/37/38 42/43

EC Safety Phrase

S 22 26 36/37/39 45

UN (DOT)

3335

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause reproductive and fetal effects. Cancer suspect agent.

Poison Class

4

Fire Fighting Measures

Flash Point

159

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents. Darkens upon exposure to light, air or moisture.

Decomposition

Carbon monoxide, oxides of nitrogen, carbon dioxide.

Transport Information

UN Number

3335

HS Code

2922 49 95