Product Identification

Product Name

2-Amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid

Synonyms

(2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine

CAS

555-30-6

Formula

C10H13NO4

Molecular Weight

211.22

EINECS

209-089-2

RTECS

AY5950000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Merck

12,6132

Beilstein/Gmelin

2417244

Beilstein Reference

4-14-00-02505

Physical and Chemical Properties

Appearance

Colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form.

Solubility in water

10 g/L

Melting Point

315 - 318

Boiling Point

165 - 168 (0.05 torr)

Usage

Antihypertensive agent.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Inhalation of dust may cause respiratory tract irritation.

Skin

May cause allergic contact dermatitis.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system effects such as psychosis, hallucinations, depression, visual changes and mental changes.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause reproductive and fetal effects.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.