Product Identification

Product Name

Ethyl methanesulfonate

Synonyms

Ethyl mesylate
Ethyl methanesulfonate
Ethylmesilate
Half-myleran
Methanesulfonic acid, ethyl ester
O-Ethyl methylsulfonate

CAS

62-50-0

Formula

C3H8O3S

Molecular Weight

124.16

EINECS

200-536-7

RTECS

PB2100000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

13,3859

Beilstein/Gmelin

773969

Beilstein Reference

4-04-00-00012

Physical and Chemical Properties

Appearance

Clear colorless liquid.

Solubility in water

Soluble

Boiling Point

213

Vapor Pressure

.34

Density

1.2079 g/cm3 (20 C)

Partition Coefficient

.09

Usage

Biochemical research.

Refractive Index

1.4194 (15 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause irritation of the digestive tract.

EC Risk Phrase

R 45 46 20/21/22

EC Safety Phrase

S 53 45

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause cancer according to animal studies.

Exposure limit(s)

OSHA: Possible Select carcinogen

Poison Class

1*

Fire Fighting Measures

Flash Point

100

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide.

Transport Information

UN Number

2810