Product Identification

Product Name

4,4'-Methylenebis(N,N-dimethylaniline)

Synonyms

4,4'-Methylenebis(N,N-dimethylaniline)
Michler's base
N,N,N',N'-Tetramethyl-4,4'-methylenedianiline
p,p'-Tetramethyldiamindiphenylmethane
Tetrabase

CAS

101-61-1

Formula

C17H22N2

Molecular Weight

254.38

EINECS

202-959-2

RTECS

BY5250000

RTECS Class

Tumorigen; Mutagen

Merck

12,6264

Beilstein/Gmelin

479956

Beilstein Reference

4-13-00-00390

EC Index Number

612-201-00-6

EC Class

carcinogenic

Physical and Chemical Properties

Appearance

Yellowish glistening leaflets or plates or tan crystals. Weak odor. Sublimes without decomposition.

Solubility in water

Insoluble

Melting Point

85 - 88

Boiling Point

390

Vapor Pressure

3E-6 (25 C)

Density

1.14 g/cm3 (20 C)

pKa/pKb

7.96 (pKb)

Partition Coefficient

4.43

Heat Of Vaporization

63.9 kJ/mol

Usage

Chemical intermediate for dyes: eg, basic yellow 2, basic orange 14, solvent yellow 34, chemical intermediate for its hydrochloride salt, reagent for lead.

Vapor Density

8.77

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Causes respiratory tract irritation.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

Overexposure may cause methemoglobinemia. Causes digestive tract irritation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 45

EC Safety Phrase

S 53 45

UN (DOT)

3259

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. Animal inhalation studies have reported the development of tumors. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.

Exposure limit(s)

OSHA: Possible Select carcinogen

Poison Class

4

Fire Fighting Measures

Flash Point

173

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Acids - acid chlorides - acid anhydrides - oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3259

Hazard Class

8

Packing Group

I; II; III

HS Code

2921 59 90