Product Identification

Product Name

2-(4-Chloro-o-tolyloxy)propionic acid

Synonyms

2-(4-Chloro-2-methylphenoxy)propanoic acid
2-(4-Chloro-o-tolyloxy)propionic acid
Compitox
Liranox
Mecoturf
Rankotex

CAS

93-65-2

Formula

C10H11ClO3

Molecular Weight

214.66

EINECS

202-264-4

RTECS

UE9750000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector

Merck

13,5807

Beilstein/Gmelin

2212752

Beilstein Reference

3-06-00-01266

EC Index Number

607-049-00-2

EC Class

Harmful; Irritant

Physical and Chemical Properties

Appearance

Colorless crystals.

Solubility in water

600 mg/L

Melting Point

92 - 94

Boiling Point

327

Density

1.35 g/cm3

pKa/pKb

3.20 (pKa)

Partition Coefficient

3.13

Usage

Selective herbicide for post-emergence control of broad-leaved weeds in wheat, barley, oats, herbage seed crops, grassland, and under fruit trees and vines, and control of docks in meadow and pastures.

Vapor Density

N/R

First Aid Measures

Ingestion

Induce vomiting with Ipecac syrup. Seek medical advice.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Do not store near heat or open flame. Protect from freezing. Storage site should be close to lab so that only small quantities required for experimentation need to be carried. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.

Skin

Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.

Eyes

Eye, nose, and mouth irritation are possible with direct contact.

Ingestion

Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 22 38 41

EC Safety Phrase

S 26 37/39

UN (DOT)

2765

Exposure Controls/Personal Protection

Personal Protection

Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Water spray, fog or regular foam.

Fire Potential

Pure mecoprop as well as commercial products are nonflammable.

Accidental Release Measures

Small spills/leaks

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Stability

It is stable to heat and resistant to redn, hydrolysis, atmospheric oxidn. Solutions of the salt of mcpp are stable for several yr under normal storage conditions. At low temperatures the salt will crystallize out of solution, but the crystals will redissolve on warming. Salts of mecoprop.

Incompatibilities

Strong oxidizing agents.

Decomposition

May give off chlorine compounds and carbon monoxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2765

Hazard Class

3.2