Product Identification

Product Name

2-Aminosuccinamic acid

Synonyms

(2S)-2,4-Diamino-4-oxobutanoic acid
a-Aminosuccinamic acid
Aspartic acid amide
Crystal VI
L-2,4-Diamino-4-oxobutanoic acid
L-Aspartamine
N,N'-Bis(trimethylsilyl)methanediimine
Thiocyanic acid, methyl ester

CAS

1000-70-0

CAS

70-47-3

Formula

C4H8N2O3

Formula

C7H18N2Si2

Molecular Weight

132.12

Molecular Weight

186.4

EINECS

200-735-9

EINECS

213-673-2

RTECS

VV1302500

RTECS Class

Other

Merck

12,872

Beilstein/Gmelin

1723527

Beilstein/Gmelin

2042082

Beilstein Reference

4-04-00-03004

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

Very soluble

Melting Point

-23

Melting Point

234-235

Boiling Point

343

Boiling Point

164

Density

0.001 g/cm3 (25 C)

Density

0.8211 g/cm3 (25 C)

pKa/pKb

2.30 (pKa)

Partition Coefficient

-2.33

Usage

A non-essential amino acid required for protein synthesis. Also used as a storage form for waste nitrogen.

Refractive Index

1.435 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Ingestion

Seek medical assistance.

Inhalation

Vapors may cause dizziness or suffocation. May cause irritation or burns.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.

Skin

May cause irritation or burns.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Remove and isolate contaminated clothing and shoes. Wash skin with soap and water. Flush with running water for at least 20 minutes

Eyes

See Skin.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Flush with running water for at least 20 minutes.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation. The toxicological properties of this material have not been fully investigated.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 22 36/38

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

1993

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

42

Fire Fighting

Use of water spray when fighting fire may be inefficient. Small Fires: Dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Large Fires: Water spray, fog or alcohol-resistant foam. Use water spray or fog; do not use straight streams.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures

Small spills/leaks

Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean non-sparking tools to collect absorbed material.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1993