Product Identification

Product Name

Riboflavin

Synonyms

6,7-Dimethyl-9-D-ribitylisoalloxazine
Beflavine
Benzo(g)pteridine-2,4(3H,10h)-dione, 7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)-6,7-dimethyl-9-d-ribitylisoalloxazine
Isoalloxazine, 7,8-dimethyl-10-D-ribityl-
Riboflavine
Vitamin B2

CAS

83-88-5

Formula

C17H20N4O6

Molecular Weight

376.37

EINECS

201-507-1

RTECS

VJ1400000

RTECS Class

Drug; Mutagen

Merck

12,8367

Beilstein/Gmelin

97825

Beilstein Reference

4-26-00-02542

Physical and Chemical Properties

Appearance

Fine orange-yellow needles. or powder.

Solubility in water

0.1 g/L

Melting Point

280

pKa/pKb

4.32 (pKa)

Partition Coefficient

-1.46

Usage

Inhibitor of poly(ethylene glycol) oxidation.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store below 40C. Store protected from light. Store in a cool, dry area away from incompatible substances.

Handling

Use with adequate ventilation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Wash clothing before reuse.

Hazards Identification

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation. Low hazard for usual industrial handling.

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Poison Class

F (Not subject to toxicity classification)

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dust can be an explosion hazard when exposed to heat or flame. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures. May decompose on exposure to moist air or water. Darkens on exposure to light.

Incompatibilities

Strong oxidizing agents, reducing agents, bases, metallic salts, calcium, moisture, direct light.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of phosphorus, carbon dioxide.

Transport Information

HS Code

2936 23 00