Product Identification

Product Name

Piperazine-1,4-bis(2-ethanesulfonic acid)

Synonyms

1,4-Piperazinebis(ethanesulfonic acid)
1,4-Piperazinebis(ethansulfonic acid)
2,2'-(Piperazine-1,4-diyl)bis(ethanesulfonic) acid
2-[4-(2-Sulfoethyl)piperazin-1-yl]ethanesulfonic acid
Piperazine-N,N'-bis(2-ethanesulfonic acid)
PIPES

CAS

5625-37-6

Formula

C8H18N2O6S2

Molecular Weight

302.36

EINECS

227-057-6

Merck

12,7633

Beilstein/Gmelin

817713

Beilstein Reference

5-23-02-00380

Physical and Chemical Properties

Appearance

White crystalline powder.

Solubility in water

Very soluble

Melting Point

300

Boiling Point

499

pKa/pKb

5.71 (pKb)

Partition Coefficient

-2.13

Usage

Biological buffer.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Disposal Code

28

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.

Transport Information

HS Code

2933 59 95