Product Identification

Product Name

Acetic acid chloride

Synonyms

Acetic acid chloride
Acetic chloride
Ethanoyl chloride

CAS

75-36-5

Formula

C2H3ClO

Molecular Weight

78.5

EINECS

200-865-6

RTECS

AO3690000

RTECS Class

Mutagen; Human Data

Merck

13,87

Beilstein/Gmelin

605303

Beilstein Reference

4-02-00-00395

EC Index Number

607-011-00-5

EC Class

Highly flammable; Reacts violently with water; Corrosive

Physical and Chemical Properties

Appearance

A colorless, fuming liquid with a pungent odor.

Solubility in water

Insoluble

Melting Point

-112

Boiling Point

50.9

Vapor Pressure

287

Density

1.13773 g/cm3 (0 C)

Heat Of Vaporization

28.64 kJ/mol

Heat Of Combustion

-1083 kJ/mol

Usage

Acetylating agent, in testing for cholesterol, determination of water in organic liq.

Vapor Density

2.7

Odor threshold

1 ppm

Refractive Index

1.38736 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.

Eyes

Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep container closed when not in use. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area. Keep away from acids. Do not store near alkaline substances. Keep away from strong bases.

Handling

Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Prevent build up of vapors to explosive concentration. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Irritation may lead to chemical pneumonitis and pulmonary edema. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause systemic effects. May cause burning sensation in the chest.

Skin

Contact with liquid is corrosive and causes severe burns and ulceration. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Contact with liquid is corrosive to the eyes and causes severe burns. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause perforation of the digestive tract. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. Ingestion of large amounts may cause CNS depression. May cause systemic effects.

Hazards

Vapor is heavier than air and may travel a considerable distance to source of ignition and flash back.

EC Risk Phrase

R 11 14 34

EC Safety Phrase

S 9 16 26 45

UN (DOT)

1717

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Poison Class

2

Fire Fighting Measures

Flash Point

5

Autoignition

390

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Contact with moisture or water may generate sufficient heat to ignite nearby combustible materials. Containers may explode in the heat of a fire. Vapors mixed with air can explode when ignited. Reacts violently with water. Extinguishing media: Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Water may be ineffective.

Upper exp. limit

19

Lower exp. limit

7.3

Fire Potential

Very flammable. Very dangerous when exposed to heat or flame; reacts violently with water.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

11

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong acids, strong bases, strong dehydrating agents, strong oxidizing agents, strong reducing agents, water and mixtures containing water (e.g. aqueous solutions, water).

Decomposition

Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.

Combustion Products

When heated to decomposition, hydrogen chloride and phosgene, extremely poisonous gases, are evolved.

Transport Information

UN Number

1717

Hazard Class

3

Packing Group

II

HS Code

2915 90 80