Product Identification

Product Name

Alloxan

Synonyms

2,4,5,6(1H,3H)-Pyrimidinetetrone
2,4,5,6-Pyrimidinetetrone
2,4,5,6-Tetraoxohexahydropyrimidine
2,4,5,6-Tetraoxypyrimidine
5,6-Dioxyuracil
Mesoxalylurea

CAS

50-71-5

Formula

C4H2N2O4

Molecular Weight

142.07

EINECS

200-062-0

RTECS

BA4200000

RTECS Class

Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Primary Irritant

Merck

13,279

Beilstein/Gmelin

132451

Beilstein Reference

5-24-09-00382

Physical and Chemical Properties

Solubility in water

Very soluble

Melting Point

289

Density

1.639 g/cm3

pKa/pKb

4.39 (pKa)

Partition Coefficient

-2.51

Heat Of Combustion

-1145 kJ/mol

Usage

Substance is used in production of diabetes in experimental animals.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

Flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

Flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2-8 C. Keep container tightly closed. May develop pressure so open carefully.

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract.

Skin

Causes irritation.

Eyes

Causes irritation.

Ingestion

Harmful if swallowed.

Hazards

Container explosion may occur under fire conditions.

EC Risk Phrase

20/21/22 36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Where compatible chemical-resistant gloves. Chemical safety goggles. Use safety shield.

Respirators

Government approved respirator.

Exposure Effects

Target organ - pancreas.

Poison Class

3

Fire Fighting Measures

Fire Fighting

Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Evacuate area. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Keep away from oxidizing materials.

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.