Product Identification

Product Name

Hexamethylenebis(5-(4-chlorophenyl)biguanide)

Synonyms

1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
1,6-Bis[5-(p-chlorophenyl)biguanidino]hexane
1,6-Di(N-p-chlorophenylbiguanidino)hexane
Bis(p-chlorophenyldiguanido)hexane
Chlorohex
Nolvasan

CAS

55-56-1

Formula

C22H30Cl2N10

Molecular Weight

505.45

EINECS

200-238-7

RTECS

DU1925000

RTECS Class

Mutagen; Reproductive Effector; Primary Irritant

Merck

12,2140

Beilstein/Gmelin

2826432

Beilstein Reference

4-12-00-01201

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

134 - 136

Boiling Point

592

Vapor Pressure

6E-14 (25 C)

pKa/pKb

2.27 (pKb)

Heat Of Vaporization

88.3 kJ/mol

Usage

Analytical standard for pharmaceuticals.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38 51/53

EC Safety Phrase

26 36/37 60 61

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Dangerous for the environment. Irritating to eyes, respiratory system and skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Photosensitizer.

Poison Class

4

Fire Fighting Measures

Flash Point

312

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.