Product Identification

Product Name

Nickel dibutyldithiocarbamate

Synonyms

(Dibutyldithiocarbamato)nickel(II)
bis(Dibutyldithiocarbamate) nickel
bis(Dibutyldithiocarbamato)nickel
NBC
Nickel dibutyldithiocarbamate
Nickel(II) dibutyldithiocarbamate

CAS

13927-77-0

Formula

C18H36N2NiS4

Molecular Weight

467.51

EINECS

237-696-2

RTECS

QR6140000

RTECS Class

Tumorigen

Beilstein/Gmelin

145496 (G)

Physical and Chemical Properties

Appearance

Dark green flakes with an amine-like odor.

Solubility in water

Negligible.

Melting Point

86 minimum

Density

1.26 g/cm3 (20 C)

Usage

Accelerator for rubber vulcanization.

First Aid Measures

Ingestion

The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move the patient to fresh air. The first phase of nickel carbonyl inhalation is deceptive in its lack of severe symptoms. Chelating agents - although penicillamine has an effect, diethyldithiocarbamate (ddc) is the preferred chelating agent in the literature. Collect an 8 hour sample immediately after exposure. Levels of: less than 10 mcg/dl: delayed symptoms are not expected. Ddc is unnecessary.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

Stool in a cool, dry location. Keep containers closed to prevent contamination.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Nausea, vomiting, and diarrhea.

Skin

Nickel contact dermatitis is the most common reaction to nickel. It is estimated that 5 percent of all eczemas are nickel reactions. Nickel itch may begin with a burning and itching sensation, followed by erythema and nodular eruptions. Once acquired, nickel sensitivity usually persists.

Eyes

Acute toxicity from nickel inhalation includes sore throat and hoarseness. There is speculation inflammation of the eye and epiphora have occurred in nickel plating work environments due to poor ventilation. Occasional exposure to nickel aerosol and other contaminants has resulted in nasal irritation, loss of smell, damage to the nasal mucosa, and perforation of the nasal septum. In rare cases, nickel workers have complained of a bitter metallic taste.

Ingestion

Large doses taken orally may cause nausea, vomiting, and diarrhea.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Not normally required. If needed, use NIOSH/MSHA approved dust respirator.

Exposure Effects

Acute intoxication of nickel carbonyl has two stages, immediate and delayed. A person may have a temperature as a delayed symptom, but it will seldom elevate above 101 degrees. Early symptoms after inhalation are dizziness, giddiness, and weakness. Nickel salts are reported to be animal teratogens. Increased incidence of stillbirth and neonatal mortality of rat offspring were associated with maternal consumption of nickel chloride solutions prior to mating and during gestation. Nickel has been found in breast milk. ORAL ADMINISTRATION of nickel sulphate to rats caused decreased testicular, prostate, and seminal vesicle size as well as abnormalities of sperm and decreased sperm count.

Exposure limit(s)

IDHL: NIOSH considers nickel metal and other compounds (as Ni) to be a potential

Poison Class

5

Fire Fighting Measures

Flash Point

>263

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Wear protective equipment. Sweep up and place in container for disposal.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Oxides of carbon, sulfur and nitrogen.

Combustion Products

Toxic gases and vapors (such as nickel carbonyl) may be released in a fire involving nickel.