Product Identification

Product Name

1-Hydrazinophthalazine hydrochloride

Synonyms

1-Hydrazinophthalazine hydrochloride
Apresoline
Hyperazin
Phthalazin-1-ylhydrazine hydrochloride

CAS

304-20-1

Formula

C8H9ClN4

Molecular Weight

196.64

EINECS

206-151-0

RTECS

TH9000000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

13,4782

Beilstein/Gmelin

3568329

Beilstein Reference

5-25-17-00412

Physical and Chemical Properties

Melting Point

273

Usage

Vasodilator agent.

First Aid Measures

Ingestion

Seek medical assistance.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.

Skin

Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.

Eyes

Immediately flush with running water for at least 20 minutes.

Hazards Identification

Ingestion

See Inhalation.

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Skin

Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.

Eyes

See Inhalation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 20/21/22 40 63

EC Safety Phrase

S 22 36/37 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Fire Fighting Measures

Fire Fighting

Extinguish using agent most appropriate for surrounding fire.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Transport Information

UN Number

2811

Stability and Reactivity

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.