Product Identification

Product Name

Gliclazide

Synonyms

1-(3,3a,4,5,6,6a-Hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea

CAS

21187-98-4

Formula

C15H21N3O3S

Molecular Weight

323.42

EINECS

244-260-5

RTECS

YT4500000

RTECS Class

Drug; Reproductive Effector; Human Data

Merck

12,4448

Beilstein/Gmelin

1657836

Beilstein Reference

6-20

Physical and Chemical Properties

Solubility in water

Slightly soluble

Melting Point

180 - 182

Density

1.319 g/cm3

pKa/pKb

7.82 (pKb)

Usage

Medicine used to help control blood sugar levels in people with type 2 diabetes.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Ingestion

May be harmful if swallowed.

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Protective gloves. Chemical safety goggles.

Respirators

Wear dust mask.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Acids, Bases, Strong oxidizing agents.

Stability

Stable at normal temperatures and pressures. Heat.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.