Product Identification

Product Name

3-(4-Aminophenyl)-3-ethyl-2,6-Piperidinedione

Synonyms

3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
3-(p-Aminophenyl)-3-ethylpiperidine-2,6-dione
Ba-16038
Cytadren
Elipten
p-Aminoglutethimide

CAS

125-84-8

Formula

C13H16N2O2

Molecular Weight

232.28

EINECS

204-756-4

RTECS

MA4026950

RTECS Class

Drug; Reproductive Effector; Human Data

Merck

12,460

Beilstein/Gmelin

210656

Beilstein Reference

5-22-13-00297

Physical and Chemical Properties

Appearance

almost white powder

Solubility in water

Insoluble

Melting Point

149 - 150

Boiling Point

457

Vapor Pressure

2E-8 (25 C)

pKa/pKb

9.59 (pKb)

Heat Of Vaporization

71.8 kJ/mol

Usage

Derivative of the sedative glutethimide. Originally introduced as an anticonvulsant.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Irritating to eyes, respiratory system and skin. Calif. Prop. 65 reproductive hazard. Target organ(s): Adrenal cortex. Thyroid.

Fire Fighting Measures

Flash Point

230

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.