Product Identification

Product Name

p-Arsanilic acid

Synonyms

1,3-Isobenzofurandione, 4-methyl-
4-Aminobenzenearsonic acid
4-Aminophenylarsonic acid
4-Methyl-2-benzofuran-1,3-dione
Aminophenylarsine acid
p-Aminobenzenearsonic acid
p-Aminophenylarsonic acid
p-Anilinearsonic acid

CAS

4792-30-7

CAS

98-50-0

Formula

C6H8AsNO3

Formula

C9H6O3

Molecular Weight

162.13999999999999

Molecular Weight

217.06

EINECS

225-344-0

EINECS

202-674-3

RTECS

CF7875000

RTECS Class

Tumorigen

Merck

12,830

Beilstein/Gmelin

128904

Beilstein/Gmelin

1102334

Beilstein Reference

4-16-00-01190

Beilstein Reference

5-17-11-00271

EC Index Number

033-002-00-5

EC Class

toxic, dangerous for the environment

Physical and Chemical Properties

Appearance

Monoclinic needles from water or alcohol. Practically odorless.

Appearance

Solid.

Solubility in water

Very soluble

Melting Point

> 300

Melting Point

118

Boiling Point

125 (0.4 torr)

Density

1.421 g/cm3

Density

1.9571 g/cm3 (20 C)

pKa/pKb

4.17 (pKa)

Usage

Production of medicinal arsenicals.

First Aid Measures

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Ingestion

Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Inhalation of arsenic compounds may lead to irritation of the respiratory tract and leading to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation.

Skin

May cause skin irritation. Exposure to arsenic compounds may produce hyperpigmentation of the skin and hyperkeratoses of plantar and palmar surfacesas well as both primary irritation and sensitization types.

Eyes

May cause eye irritation. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours.

EC Risk Phrase

R 23/25 50/53

EC Safety Phrase

S 20/21 28.1 45 60 61

UN (DOT)

3280

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Exposure Effects

May cause liver and kidney damage. Chronic exposure to arsenical dust may cause breath shortness, nausea, chest pains, and garlic odor. Cancer suspect agent.

Poison Class

1

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Yields flammable vapors on heating above melting point.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen, oxides of arsenic.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3280

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2931 00 95