Product Identification

Product Name

1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile

Synonyms

1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
Cipram
Nitalapram

CAS

59729-33-8

Formula

C20H21FN2O

Molecular Weight

324.39999999999998

EINECS

261-891-1

RTECS

NP6313500

RTECS Class

Drug; Human Data

Merck

12,2379

Beilstein/Gmelin

1397373

Beilstein Reference

5-18-12-00271

Physical and Chemical Properties

Solubility in water

Slightly soluble

Boiling Point

428

Vapor Pressure

2E-7 (25 C)

pKa/pKb

4.31 (pKb)

Heat Of Vaporization

68.5 kJ/mol

Usage

Selective serotonin uptake inhibitor. Antidepressant.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Protective gloves. Chemical safety goggles.

Respirators

Wear dust mask.

Exposure Effects

Avoid contact and inhalation.

Fire Fighting Measures

Flash Point

213

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.