Product Identification

Product Name

Ampicillin

Synonyms

(2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid triydrate
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)- 3,3-dimethyl-7-oxo-, trihydrate, D- (-)
Amcill
Principen

CAS

7177-48-2

Formula

C16H25N3O7S

Molecular Weight

403.46

RTECS

XH8425000

RTECS Class

Tumorigen; Drug; Reproductive Effector

Beilstein/Gmelin

5399534

Physical and Chemical Properties

Appearance

Odorless white microcrystalline powder with a bitter taste.

Melting Point

198

pKa/pKb

2.5 (COOH)(at 25℃) (pKa)

Heat Of Vaporization

Usage

Antibiotic.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause allergic respiratory reaction. May cause respiratory tract irritation.

Skin

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause skin rash and eruptions.

Eyes

Causes eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. Ampicillin (a penicillin class antibiotic) exposure may cause adverse effects in certain individuals. These can include; central nervous system toxicity (including hallucinations, confusion, unconsciousness, and seizures), hypersensitivity reactions, and blood cell

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause reproductive and fetal effects.

Fire Fighting Measures

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizers.

Decomposition

Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.