Product Identification

Product Name

N-(2-Methylphenyl)thiourea

Synonyms

(2-Methylphenyl)thiourea
N-(o-Tolyl)thiourea
o-Tolylthiourea

CAS

614-78-8

Formula

C8H10N2S

Molecular Weight

166.24

EINECS

210-395-3

RTECS

YU2975000

RTECS Class

Agricultural Chemical and Pesticide

Beilstein/Gmelin

2086802

Beilstein Reference

4-12-00-01766

Physical and Chemical Properties

Appearance

Crystalline solid.

Solubility in water

Slightly soluble

Melting Point

160

Boiling Point

295

pKa/pKb

13.14 pKa

Partition Coefficient

1.96

First Aid Measures

Ingestion

Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See inhalation.

Inhalation

The material is highly toxic if orally ingested.

Skin

Thiourea compounds frequently cause allergic contact dermatitis.

Eyes

See inhalation

Hazards

When heated to decomposition, it emits very toxic fumes of oxides of nitrogen and sulfur.

EC Risk Phrase

R 25

EC Safety Phrase

S 22 36/37 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Fire Fighting Measures

Fire Fighting

(Non-Specific -- Poisonous Solid, n.o.s.) Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.(Non-Specific -- Poisonous Solid, n.o.s.) For small fires use dry chemical, carbon dioxide, water spray, or foam. Use water spray, fog, or foam on larger fires. Move container from fire area if you can do so without risk.

Accidental Release Measures

Small spills/leaks

(Non-Specific -- Poisonous Solid, n.o.s.) Keep unnecessary people away, isolate hazard area and deny entry. Stay upwind and keep out of low areas. Do not touch spilled material, stop leak if you can do so without risk. Absorb small spills with sand or other noncombustible material and place into containers for later disposal. For large spills, dike far ahead of spill for later disposal.

Stability and Reactivity

Incompatibilities

Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents Reactions with these materials generate heat and in many cases hydrogen gas.

Stability

No data.

Transport Information

UN Number

2811