Product Identification

Product Name

Thymolphthalein

Synonyms

1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-
2',2''-Diisopropyl-5',5''-dimethylphenolphthalein
3,3-Bis(4-hydroxy-3-isopropyl-6-methyl)phthalide

CAS

125-20-2

Formula

C28H30O4

Molecular Weight

430.55

EINECS

204-729-7

Merck

12,9542

Beilstein/Gmelin

359413

Beilstein Reference

5-18-04-00194

Physical and Chemical Properties

Appearance

White powder or crystals, odorless.

Solubility in water

Insoluble

Melting Point

253

pKa/pKb

9.90 (pKa)

Partition Coefficient

7.54

Usage

Used as a ph indicator: colorless 9.3 To blue 10.5.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation.

Hazards Identification

Ingestion

The toxicological properties of this substance have not been fully investigated.

Inhalation

Inhalation of dust may cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

Dust may cause mechanical irritation.

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

3

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizers.

Decomposition

Carbon monoxide, carbon dioxide.

Transport Information

HS Code

2932 29 80