Product Identification

Product Name

3-Methylpyridine

Synonyms

3-Picoline
m-Picoline

CAS

108-99-6

Formula

C6H7N

Molecular Weight

93.13

EINECS

203-636-9

RTECS

TJ5000000

RTECS Class

Tumorigen; Primary Irritant

Merck

12,7555

Beilstein/Gmelin

1366

Beilstein Reference

5-20-05-00506

EC Class

flammable, harmful, irritant

Physical and Chemical Properties

Appearance

Colorless liquid with an unpleasant odor.

Solubility in water

Soluble

Melting Point

-19.4

Boiling Point

141 - 143

Vapor Pressure

4.5 (20 C)

Density

0.957 g/cm3 (20 C)

pKa/pKb

8.32 (pKb)

Partition Coefficient

1.29

Heat Of Vaporization

37.4 kJ/mol

Heat Of Combustion

-3432 kJ/mol

Usage

Solvent, intermediate in dye and resins industries, in manufacture of insecticides, waterproofing agents, niacin and niacinamide.

Vapor Density

3.21

Refractive Index

1.5043 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes irritation of mucous membrane. Vapors may cause dizziness or suffocation. Exposure may give rise to flushing of face, skin rash, an increase in heart and respiration rates, headaches, giddiness, nausea, and vomiting.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

May cause irritation of the digestive tract. Intoxication may include weight loss, diarrhea, weakness, ataxia, and unconsciousness.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 20/21/22 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2313

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation. <br>Animal studies on chick for substituted pyridines have shown teratogenicity. Injected chicken eggs develop leg and skeletal malformations.

Exposure limit(s)

PDK (as mixture of isomers): 5 mg/m3 (USSR 1991).

Poison Class

3

Fire Fighting Measures

Flash Point

36

Autoignition

537

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water. For large fires, use water spray, fog or regular foam. For small fires, use dry chemical, carbon dioxide, water spray or regular foam.

Upper exp. limit

8.7

Lower exp. limit

1.3

Fire Potential

This chemical is flammable.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.

Stability and Reactivity

Disposal Code

5

Incompatibilities

Oxidizing agents, hydrogen peroxide, iron (III) sulfate, sulfuric acid

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2313

Hazard Class

3

Packing Group

III

HS Code

2933 39 99