Difluorochloromethane(75-45-6)
Product Identification
Product Name
Difluorochloromethane
Synonyms
Difluorochloromethane
Freon 22
Monochlorodifluoromethane
Refrigerant gas R-22
CAS
75-45-6
Formula
CHClF2
Molecular Weight
86.47
EINECS
200-871-9
RTECS
PA6390000
RTECS Class
Tumorigen; Mutagen; Reproductive Effector
Beilstein/Gmelin
1731036
Beilstein Reference
4-01-00-00032
Physical and Chemical Properties
Appearance
Chlorodifluoromethane is a colorless gas with an ethereal odor.
Solubility in water
3 g/L
Melting Point
-157.4
Boiling Point
-40.8
Vapor Pressure
6290 (25 C)
Density
1.41 g/cm3 (20 C)
Partition Coefficient
1.08
Heat Of Vaporization
20.8 kJ/mol
Usage
Propellant, fumigant, insecticide.
Vapor Density
2.98
Refractive Index
1.264 (22 C)
First Aid Measures
Ingestion
These substances may cause frostbite to the upper airway and gastrointestinal tract after ingestion. Administer oxygen and manage airway as clinically indicated. Emesis, activated charcoal, and gastric lavage are not recommended.
Inhalation
Provide a quiet calm atmosphere to prevent adrenaline surge if the patient is seen before the onset of cardiac arrhythmias. Minimize physical exertion.
Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. If frostbite has occurred, refer to dermal treatment in the main body of this document for rewarming.
Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Ophthamologic consultation should be obtained in any symptomatic patients.
Handling and Storage
Storage
Keep container tightly closed. Keep away from heat, sparks and flames.
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
Hazards Identification
Inhalation
Pulmonary irritation, bronchial constriction, cough, dyspnea, and chest tightness may develop after inhalation. Chronic pulmonary hyperreactivity may occur. Adult respiratory distress syndrome has been reported following acute inhalational exposures. Pulmonary edema is an autopsy finding in fatal cases.
Skin
Dermal contact may result in defatting, irritation or contact dermatitis. Severe frostbite has been reported as an effect of freon exposure. Injection causes transient pain, erythema and edema.
Eyes
EYES - Eye irritation occurs with ambient exposure. Frostbite of the lids may be severe. NOSE - Nasal irritation occurs with ambient exposure. THROAT - Irritation occurs. Frostbite of the lips, tongue, buccal mucosa and hard palate developed in a man after deliberate inhalation.
Ingestion
Nausea may develop. Ingestion of a small amount of trichlorofluoromethane resulted in necrosis and perforation of the stomach in one patient.
Hazards
Vapors from liquefied gas are initially heavier than air and spread along ground.
UN (DOT)
1018
Exposure Controls/Personal Protection
Personal Protection
Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Exposure Effects
Headache, dizziness, and disorientation are common. Cerebral edema may be found on autopsy. Dichlorodifluoromethane was not teratogenic in rats and rabbits. <br>The reproductive effects of 1,1,1,2-tetrafluoroethane were studied in rats. No adverse effects on reproductive performance was noted or on the development, maturation or reproductive performance of up to two successive generations.
Exposure limit(s)
TLV (as TWA): 1000 ppm; 3540 mg/m3 (ACGIH 1992-1993). MAK: 500 ppm; 1800 mg/m3; IV, C (1992). NIOSH REL: TWA 1000 ppm (3500 mg/m3) ST 1250 ppm (4375 mg/m3)
Poison Class
5
Fire Fighting Measures
Flash Point
-78
Autoignition
632
Fire Fighting
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Upper exp. limit
26.9
Fire Potential
Slightly flammable.
Stability and Reactivity
Incompatibilities
Incompatible with alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc).
Stability
Stable at normal temperatures and pressure.
Decomposition
Decomposition gases are toxic and irritating. When heated to decomp. They evolve highly toxic. Fumes of hydrogen chloride and hydrogen fluoride. All fluorocarbons will undergo thermal decomposition when exposed to flame or red-hot metal. Decomposition products of the chlorofluorocarbons will include hydrofluoric and hydrochloric acid along with smaller amounts of phosgene and carbonyl fluoride. The last compound is very unstable to hydrolysis and quickly changes to hydrofluoric acid and carbon dioxide in the presence of moisture.
Combustion Products
Decomposition gases are toxic and irritating.