Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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5-Ethyl-5-(1-methylbutyl)barbituric acid(76-74-4)

Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Product Identification

Product Name

5-Ethyl-5-(1-methylbutyl)barbituric acid

Synonyms

5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)malonylurea
5-Ethyl-5-(sec-pentyl)barbituric acid
Barpental
Ethaminal
Mebubarbital

CAS

76-74-4

Formula

C11H18N2O3

Molecular Weight

226.28

EINECS

200-983-8

RTECS

CQ5775000

RTECS Class

Drug; Reproductive Effector; Human Data

Merck

12,7272

Beilstein/Gmelin

87067

Beilstein Reference

5-24-09-00168

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Physical and Chemical Properties

Appearance

White to practically white, fine, powder. Practically odorless.

Solubility in water

Insoluble

Melting Point

129-130

Boiling Point

506

pKa/pKb

7.88 (pKa)

Partition Coefficient

2.1

Heat Of Vaporization

Usage

This is a drug of abuse.

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First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

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Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

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Hazards Identification

Inhalation

Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.

Skin

Erythematous or hemorrhagic blisters (barb - burns) may occasionally occur on the hands, buttocks, in between the knees, and at any pressure point.

Ingestion

Respiratory arrest may occur following severe intoxication. Aspiration pneumonia has been reported, in barbiturate ingestions, following vomiting of gastric contents.

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Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

CNS findings range from drowsiness to deep coma. Seizures are not expected, except upon withdrawal from barbiturate dependence.

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Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

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Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

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Stability and Reactivity

Stability

Aq solution of pentobarbital sodium are not Pentobarbital sodium sensitive to air and moisture pentobarbital sodium alkaline solution decomp on storage and heating.

Incompatibilities

Strong oxidizing agents.