Product Identification

Product Name

4-Methyl-7-(diethylamino)coumarin

Synonyms

(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
10,11-Dihydroquinidine
7-(Diethylamino)-4-methyl-2H-1-benzopyran-2-one
7-(Diethylamino)-4-methylcoumarin
7-Methyl-7-(diethylamino)coumarin
C.I. 551100
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
Dihydroquinidine
Fluorescent Brightener 52
Hydroconquinine
Whitefluor B

CAS

1435-55-8

CAS

91-44-1

Formula

C14H17NO2

Formula

C20H26N2O2

Molecular Weight

231.32

Molecular Weight

326.44

EINECS

202-068-9

EINECS

215-862-5

RTECS

GN6370000

RTECS

MX3016000

RTECS Class

Drug

RTECS Class

Drug; Human Data

Merck

13,4831

Beilstein/Gmelin

193303

Beilstein/Gmelin

91441

Beilstein Reference

5-18-11-00445

Beilstein Reference

5-23-13-00340

Physical and Chemical Properties

Appearance

Light tan grains. Gives bright blue-white fluorescence in very dilute solutions.

Solubility in water

Insoluble

Melting Point

169 - 170

Melting Point

71.7

Boiling Point

240 - 243 (7 torr)

Boiling Point

498

Vapor Pressure

9E-11 (25 C)

pKa/pKb

8.14 (pKb)

pKa/pKb

4.06 (pKb)

Heat Of Vaporization

80.7 kJ/mol

Usage

Antiarrhythmic medication.

Usage

Optical bleach in textile industry, in coatings for paper, labels, book covers, etc, invisible marking agent, to lighten plastics, resins, varnishes & lacquers.

Vapor Density

8

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Ingestion

Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place.

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. No special precautions indicated.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation. The toxicological properties of this material have not been fully investigated.

Ingestion

May cause irritation of the digestive tract. Low hazard for usual industrial handling.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22

EC Safety Phrase

36/37

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

The toxicological properties of this material have not been investigated.

Exposure Effects

Toxic. Toxic by inhalation, in contact with skin and if swallowed.

Fire Fighting Measures

Flash Point

255

Autoignition

430

Fire Fighting

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.