Product Identification

Product Name

Tris(2-methyl-1-aziridinyl)phosphine oxide

Synonyms

Aziridine, 1,1',1''-phosphinylidynetris[2-methyl-
Methyl aphoxide
Trimethylaziridinylphosphine oxide
Tris(2-methyl-1-aziridinyl)phosphine oxide
Tris(2-methylaziridin-1-yl)phosphine oxide
Tris(methylaziridinyl)phosphine oxide

CAS

57-39-6

Formula

C9H18N3OP

Molecular Weight

215.24

EINECS

200-326-5

RTECS

SZ1925000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

12,5998

Beilstein/Gmelin

1345447

Physical and Chemical Properties

Appearance

White to straw colored liquid with a strong ammonia-like odor.

Solubility in water

Soluble

Boiling Point

90

Vapor Pressure

1 (25 C)

Density

1.079 g/cm3 (25 C)

pKa/pKb

6.78 (pKb)

Usage

Chemosterilant.

First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

Store in a cool, dry location - 18 C or below at all times.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Severely irritating, shortness of breath, decreased vital capacity, albuminara and sterility.

Skin

Causes burns.

Eyes

Contact may cause cornea damage.

Ingestion

Nausea, vomiting. See inhalation.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

NIOSH/MSHA approved respirator with an organic vapor cartridge.

Exposure Effects

Effects may be delayed.

Poison Class

1*

Fire Fighting Measures

Flash Point

150

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Use water spray to disperse vapors. Use water spray to protect workers. Wear full protective equipment during cleanup. For spills, spread absorbant over spill. Shovel material into approved collection drum.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides and amines.