Product Identification

Product Name

1(3-chloro-2-hydroxypropyl)-2-methyl-5-nitro imidazole

Synonyms

(+/-)-Tiberal
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
1-Chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol
a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol

CAS

16773-42-5

Formula

C7H10ClN3O3

Molecular Weight

219.63

EINECS

240-826-0

RTECS

NI5460000

RTECS Class

Drug; Mutagen; Reproductive Effector

Merck

12,7000

Beilstein/Gmelin

614299

Beilstein Reference

5-23-05-00072

Physical and Chemical Properties

Solubility in water

Slightly soluble

Melting Point

85.4

Boiling Point

443

Vapor Pressure

1E-8 (25 C)

pKa/pKb

11.28 (pKb)

Heat Of Vaporization

73.9 kJ/mol

Usage

An antiprotozoal compound for treatment of trichomonas vaginalis infection.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Hazards Identification

Inhalation

May be harmful if inhaled.

Skin

May be harmful if absorbed through the skin.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

22

EC Safety Phrase

36

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Harmful. Harmful if swallowed. Avoid contact and inhalation.

Fire Fighting Measures

Flash Point

222

Fire Fighting

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.