Product Identification

Product Name

2,2,2-Trifluoroethanol

Synonyms

,2,2-Trifluoroethyl alcohol
2(3H)-Benzofuranone, 5-hydroxy-
5-Hydroxy-2-coumaranone
5-Hydroxy-3H-1-benzofuran-2-one
5-Hydroxybenzofuran-2-one
b,b,b-Trifluoroethyl alcohol
TFE

CAS

2688-48-4

CAS

75-89-8

Formula

C2H3F3O

Formula

C8H6O3

Molecular Weight

100.04

Molecular Weight

150.13

EINECS

200-913-6

EINECS

220-252-7

RTECS

KM5250000

RTECS Class

Drug; Mutagen; Reproductive Effector; Primary Irritant

Beilstein/Gmelin

1733203

Beilstein/Gmelin

128621

Beilstein Reference

4-01-00-01370

Beilstein Reference

5-18-01-00258

EC Class

flammable, harmful, irritant

Physical and Chemical Properties

Appearance

Beige solid.

Appearance

Clear, colorless liquid.

Solubility in water

Soluble

Melting Point

200

Melting Point

-43.5

Boiling Point

316

Boiling Point

74.1

Vapor Pressure

71 (25 C)

Density

1.39 g/cm3

Density

1.54 g/cm3

pKa/pKb

12.46 (pKa)

Partition Coefficient

1.04

Heat Of Vaporization

42.9 kJ/mol

Refractive Index

1.2921 (24 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

May cause skin irritation.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

May cause eye irritation.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Flammables-area. Keep containers tightly closed.

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema.

Skin

Causes skin irritation. May be absorbed through the skin in harmful amounts.

Eyes

Causes severe eye irritation. May result in corneal injury.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 20/21/22 36/37/38

EC Safety Phrase

S 16 23 26 36/37/39

UN (DOT)

1987

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Poison Class

2

Fire Fighting Measures

Flash Point

33

Autoignition

480

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Upper exp. limit

28.8

Lower exp. limit

8.4

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

2

Incompatibilities

Oxidizing agents, strong bases, sodium, potassium, moisture.

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, carbon dioxide, hydrogen fluoride.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1987

Hazard Class

3

Packing Group

I; II; III

HS Code

2905 59 10