Product Identification

Product Name

1,2-Dichloro-3-isocyanatobenzene

Synonyms

1,2-Dichloro-3-isocyanatobenzene

CAS

41195-90-8

Formula

C7H3Cl2NO

Molecular Weight

188.01

EINECS

255-253-1

Beilstein/Gmelin

4669222

Physical and Chemical Properties

Appearance

Light yellow liquid.

Solubility in water

Insoluble

Boiling Point

247

Vapor Pressure

0.03 (25 C)

Density

1.42 g/cm3 (20 C)

Partition Coefficient

3.71

Heat Of Vaporization

48.4 kJ/mol

Vapor Density

6.48

Refractive Index

1.58 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture.

Handling

Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Use only in a chemical fume hood. Wash clothing before reuse. Keep from contact with moist air and steam.

Hazards Identification

Inhalation

Causes respiratory tract irritation. May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. Lachrymator.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May cause nausea and vomiting.

Hazards

Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.

EC Risk Phrase

R 23/25 36/37/38 42

EC Safety Phrase

S 23 26 36/37/39 45

UN (DOT)

2250

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Repeated exposure may cause allergic respiratory reaction (asthma).

Fire Fighting Measures

Flash Point

95

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Hydrogen chloride, hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.

Transport Information

UN Number

2250

Hazard Class

6.1

Packing Group

II