Product Identification

Product Name

4,4'-Isopropylidenediphenol

Synonyms

4,4'-(1-Methylethylidene)bisphenol
4,4'-Isopropylidenediphenol
4-[2-(4-Hydroxyphenyl)propan-2-yl]phenol

CAS

80-05-7

Formula

C15H16O2

Molecular Weight

228.29

EINECS

201-245-8

RTECS

SL6300000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Primary Irritant

Merck

13,1296

Beilstein/Gmelin

1107700

Beilstein Reference

4-06-00-06717

EC Index Number

604-030-00-0

EC Class

Irritant; Sensitising

Physical and Chemical Properties

Appearance

White crystalline solid or flakes with a mild phenolic odor.

Solubility in water

Insoluble

Melting Point

155

Boiling Point

401

Vapor Pressure

5E-7 (25 C)

Density

1.205 g/cm3

pKa/pKb

9.73 (pKa)

Partition Coefficient

3.32

Heat Of Vaporization

67.7 kJ/mol

Heat Of Combustion

-7826 kJ/mol

Usage

As fungicide.

Saturation Concentration

Approximately zero at 25 C.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Causes upper respiratory tract irritation. Causes irritation of the mucous membrane. Inhalation of dust may cause irritation of the nose and throat. Inhalation may cause liver, kidney, and bladder effects.

Skin

Causes mild skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.

Eyes

May result in corneal injury. Causes severe eye irritation and possible injury.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may produce central nervous system depression, headache, dizziness, diarrhea, and possible hemorrhagic gastroenteritis.

Hazards

This compound may form explosive dust clouds. Static electricity can cause its dust to explode.

EC Risk Phrase

R 36/37/38 43

EC Safety Phrase

S 24 26 37

UN (DOT)

2924

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Laboratory experiments have resulted in mutagenic effects. Repeated skin exposure may produce photoallergic contact dermatitis with persistent light reactivitiy.

Poison Class

4

Fire Fighting Measures

Flash Point

227

Autoignition

510

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dusts may be combustible when exposed to heat, flame, or oxidizing agents. Extinguishing media: Use agent most appropriate to extinguish fire. Use dry chemical, carbon dioxide, or appropriate foam.

Upper exp. limit

4

Lower exp. limit

.6

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Oxidizing agents, bases, acid anhydrides, acid chlorides.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, aldehydes.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2924

Hazard Class

3

Packing Group

I; II; III

HS Code

2907 23 00