Product Identification

Product Name

9,10-Secocholesta-5,7,10(19)-trien-3beta-ol

Synonyms

9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3.beta.,5Z,7E)-
Arachitol
Cholecalciferol
Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
D3-Vigantol
o-Fluorobenzaldehyde

CAS

67-97-0

CAS

446-52-6

Formula

C27H44O

Formula

C7H5FO

Molecular Weight

384.65

Molecular Weight

124.11

EINECS

200-673-2

EINECS

207-171-2

RTECS

CU6140000

RTECS

VS2900000

RTECS Class

Other

RTECS Class

Reproductive Effector; Human Data

Merck

12,10157

Beilstein/Gmelin

1916508

Beilstein/Gmelin

507155

Beilstein Reference

4-07-00-00559

EC Index Number

603-180-00-4

EC Class

very toxic

EC Class

flammable, harmful, irritant

Physical and Chemical Properties

Appearance

Colorless liquid.

Appearance

Fine colorless crystals.

Solubility in water

Insoluble

Solubility in water

Slightly soluble

Melting Point

-44.5

Melting Point

84 - 87

Boiling Point

175

Vapor Pressure

1.2 (25 C)

Density

1.161 g/cm3 (15 C)

Partition Coefficient

1.79

Heat Of Vaporization

41.2 kJ/mol

Usage

Medication.

Vapor Density

4.3

Refractive Index

1.507 (15 C)

Refractive Index

1.5204 (82 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

May cause respiratory tract irritation. Vapors may cause dizziness or suffocation.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Inhalation

Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear.

Skin

May cause skin irritation.

Skin

Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

May cause eye irritation.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light and air.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May be fatal if swallowed. May cause irritation of the digestive tract. May cause kidney damage. May cause cardiac disturbances. Ingestion may lead to mental retardation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 36/37/38

EC Risk Phrase

R 24/25 26 48/25

EC Safety Phrase

S 22 28.1 36/37 45

EC Safety Phrase

S 26 36

UN (DOT)

1989

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Chronic ingestion may cause effects similar to those of acute ingestion.

Poison Class

2

Fire Fighting Measures

Flash Point

55

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Small spills/leaks

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Incompatibilities

Oxidizing agents, reducing agents, strong bases.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - acid chlorides - acid anhydrides.

Decomposition

Carbon monoxide, carbon dioxide.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1989

UN Number

2811

Hazard Class

3

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2913 00 00

HS Code

2936 29 90