Product Identification

Product Name

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

Synonyms

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
N-(4-Hydroxy-3-methoxy)benzyl-8-methylnon-trans-6-enamide
Styptysat
trans-8-Methyl-n-vanillyl-6-nonenamide

CAS

404-86-4

Formula

C18H27NO3

Molecular Weight

305.42

EINECS

206-969-8

RTECS

RA8530000

RTECS Class

Tumorigen; Mutagen; Natural Product

Merck

12,1811

Beilstein/Gmelin

2816484

Beilstein Reference

4-13-00-02588

Physical and Chemical Properties

Appearance

Monoclinic, rectangular plates, scales from petroleum ether.

Solubility in water

practically insoluble in cold water

Melting Point

66.1

Boiling Point

210-220 (0.01 torr):

Partition Coefficient

3.04

Usage

Flavoring agent in foods, additive to topical creams, used in pepper mace.

First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Capsaicin vapors, especially from burning, may cause significant pulmonary irritation and prolonged cough. Pulmonary edema and bronchospasm may occur.

Skin

Irritation, erythema, and burning pain without vesiculation often occurs when applied topically to human skin.

Ingestion

Biting plants which contain capsaicin may cause acute stinging of the lips, tongue, and oral mucosa, which may lead to vomiting and diarrhea. Epithelial cell sloughing or mild mucosal bleeding may occur.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

stimulates pain fibers and release immunoreactive somatostatin.

Poison Class

2

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.