Product Identification

Product Name

2-Pyrrolidinecarboxylic acid

Synonyms

(S)-Proline
2-Pyrrolidinecarboxylic acid
FEMA number 3319
Pro (Iupac abbreviation)
Proline

CAS

147-85-3

Formula

C5H9NO2

Molecular Weight

115.13

EINECS

205-702-2

RTECS

TW3584000

RTECS Class

Mutagen

Merck

12,7963

Beilstein/Gmelin

80810

Beilstein Reference

5-22-01-00031

Physical and Chemical Properties

Appearance

Flat needles from alcohol-ether; prisms from water.

Solubility in water

127 g/100 ml (0 C)

Melting Point

149

Boiling Point

245

Vapor Pressure

0.006 (25 C)

Density

1.35 g/cm3 (25 C)

pKa/pKb

2.35 (pKa)

Partition Coefficient

-2.37

Heat Of Combustion

-2746 kJ/mol

Usage

Nutrient &or dietary supplement food additive.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

The toxicological properties of this substance have not been fully investigated.

Skin

Low hazard for usual industrial handling.

Eyes

No information regarding eye irritation and other potential effects was found. Contact may cause transient eye irritation.

Ingestion

The toxicological properties of this substance have not been fully investigated.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause irritation of the eyes, skin and respiratory tract. Expected to be a low ingestion hazard.

Fire Fighting Measures

Flash Point

106

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Combustion generates toxic fumes. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

31

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizers.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

HS Code

2933 99 90