Product Identification

Product Name

11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid

Synonyms

Alprostadil
Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, l
Prost-13-en-1-oic acid
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)-
Prostin VR Pediatric
SEPA-prostaglandin E1

CAS

745-65-3

Formula

C20H34O5

Molecular Weight

354.48

EINECS

212-017-2

RTECS

GY4569800

RTECS Class

Mutagen; Reproductive Effector; Human Data; Hormone

Merck

12,8063

Beilstein/Gmelin

1890728

Physical and Chemical Properties

Appearance

White solid.

Melting Point

115-116

Usage

Dilatation of ductus arteriosus in infants with ductal dependent congenital heart defects.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Harmful if swallowed. Causes gastrointestinal tract irritation.

Inhalation

The toxicological properties of this substance have not been fully investigated.

Skin

No information regarding skin irritation and other potential effects was found.

Eyes

No information regarding eye irritation and other potential effects was found.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water fog, dry chemical, carbon dioxide, or regular foam.

Accidental Release Measures

Small spills/leaks

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, carbon dioxide.