Product Identification

Product Name

Genistein

Synonyms

4',5,7-Trihydroxyisoflavone
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
5,7,4'-Trihydroxyisoflavone
Baichanin A
C.I. 75610
Sophoricol

CAS

446-72-0

Formula

C15H10O5

Molecular Weight

270.24

EINECS

207-174-9

RTECS

NR2392000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

13,4402

Beilstein/Gmelin

263823

Beilstein Reference

5-18-04-00594

Physical and Chemical Properties

Appearance

odorless yellow-white powder

Solubility in water

Insoluble

Melting Point

297-298

pKa/pKb

7.08 (pKa)

Partition Coefficient

2.84

Usage

Chemical probe to explore signal transduction pathways.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Refrigerator (approx 4 C).

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed.

Inhalation

May cause respiratory tract irritation. May be harmful if inhaled.

Skin

May cause skin irritation. May be harmful if absorbed through the skin. May cause allergic dermatitis called nickel itch. Symptoms may include burns and ulceration of skin.

Eyes

May cause eye irritation.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, carbon dioxide.