Product Identification

Product Name

2-Hydroxy-N,N,N-trimethylethanaminium chloride

Synonyms

(2-Hydroxyethyl)trimethylammonium chloride
2-Hydroxyethyl-trimethylazanium chloride
2-Hydroxy-N,N,N-trimethylethanaminium chloride
Ethanaminium
Hepacholine
Lipotril

CAS

67-48-1

Formula

C5H14ClNO

Molecular Weight

139.63

EINECS

200-655-4

RTECS

KH2975000

RTECS Class

Mutagen

Merck

13,2226

Beilstein/Gmelin

3563126

Beilstein Reference

4-04-00-01443

Physical and Chemical Properties

Appearance

White crystals. Practically neutral aqueous solution.

Solubility in water

Miscible

Melting Point

244-247

Density

1.205 g/cm3

Usage

Medication.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling.

Skin

May cause skin irritation. Low hazard for usual industrial handling.

Eyes

May cause eye irritation.

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.

Hazards

This chemical is relatively nonflammable.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Low heart rate has been reported with severe poisoning. Seizure and coma have been reported in fatal cases.

Poison Class

5

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.