Product Identification

Product Name

2,4-Diisocyanatotoluene

Synonyms

2,4-Diisocyanato-1-methylbenzene
2,4-Diisocyanatotoluene
2,4-Tolyenediisocyanate
4-Methyl-m-phenylene diisocyanate
Heylene tlc
TDI

CAS

584-84-9

Formula

C9H6N2O2

Molecular Weight

174.16

EINECS

209-544-5

RTECS

CZ6300000

RTECS Class

Tumorigen; Mutagen; Human Data; Primary Irritant

Merck

12,9668

Beilstein/Gmelin

744602

Beilstein Reference

4-13-00-00243

EC Index Number

615-006-00-4

EC Class

Carcinogenic Category 3; Very toxic; Irritant; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Water white to pale yellow liquid or crystals with a sweet, fruity, pungent odor. Darkens on exposure to sunlight.

Solubility in water

Insoluble

Melting Point

21

Boiling Point

251

Vapor Pressure

0.008 (25 C)

Density

1.218 g/cm3 (20 C)

Heat Of Vaporization

40.61 kJ/mol

Heat Of Combustion

-4126 kJ/mol

Usage

Chemical intermediate.

Saturation Concentration

33 ppm (25 C)

Odor threshold

0.4-2.14 ppm

Refractive Index

1.5678 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if symptoms occur.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store under an inert atmosphere.

Handling

Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid breathing dust, vapor, mist, or gas. Do not allow contact with water.

Hazards Identification

Inhalation

May be fatal if inhaled. Causes respiratory tract irritation.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

Causes gastrointestinal tract irritation.

Hazards

When heated to decomposition it emits very toxic fumes of cyanide and nitrogen oxides. Reacts violently with amines, alcohol, bases and warm water causing fire and explosion hazards. Avoid strong oxidizers, water, acids, bases, amines, etc., cause foam and splatter. Avoid heating. Hazardous polymerization may occur. Concentrated alkaline compound such as sodium hydroxide or tertiary amines may cause run-away polymerization. Slow, not hazardous polymerization may occur above 235F.

EC Risk Phrase

R 26 36/37/38 40 42/43 52/53

EC Safety Phrase

S 23 36/37 45 61

UN (DOT)

2078

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

Acute exposures may produce headache, insomnia, euphoria, ataxia, anxiety neurosis with depression, paranoid tendencies, or impotence. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.

Exposure limit(s)

NIOSH REL: Ca See Appendix A OSHA PEL: C 0.02 ppm (0.14 mg/m3) IDLH Ca [2.5 ppm]

Poison Class

2

Fire Fighting Measures

Flash Point

127

Autoignition

> 620

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For large fires, use water spray or fog. Do NOT get water inside containers. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. For small fires, use dry chemical or carbon dioxide.

Upper exp. limit

9.5

Lower exp. limit

.9

Fire Potential

Slightly flammable. Combustible when exposed to heat or flame.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Do not expose spill to water. Do not get water inside containers.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Alcohols - strong bases - amines - acids - heat - light - strong oxidizing agents - moisture.

Stability

Stable under normal temperatures and pressures.

Decomposition

Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Toxic oxides of nitrogen are produced during combustion of this material.

Transport Information

UN Number

2078

Hazard Class

6.1

Packing Group

II

HS Code

2929 10 10