Product Identification

Product Name

p-Toluic acid methyl ester

Synonyms

4-(Methoxycarbonyl)toluene
Benzoic acid, 4-methyl-, methyl ester
Methyl 4-toluate
p-Carbomethoxytoluene
p-Toluic acid, methyl ester

CAS

99-75-2

Formula

C9H10O2

Molecular Weight

150.19

EINECS

202-784-1

RTECS

XU2150000

RTECS Class

Primary Irritant

Beilstein/Gmelin

1100609

Beilstein Reference

4-09-00-01726

EC Class

irritant

Physical and Chemical Properties

Appearance

Opaque colorless to white shiny crystalline solid. Intense unpleasant odor.

Solubility in water

Insoluble

Melting Point

33 - 34

Boiling Point

217

Vapor Pressure

0.1 (25 C)

Density

1.06 g/cm3

Partition Coefficient

2.65

Heat Of Vaporization

45.9 kJ/mol

Heat Of Combustion

-688 kJ/mol

Usage

Organic synthesis.

Vapor Density

4.7

First Aid Measures

Ingestion

Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

UN (DOT)

3335

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

89

Autoignition

499

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Material will burn in a fire. Use water spray to keep fire-exposed containers cool. Extinguishing media: Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Upper exp. limit

9.5

Lower exp. limit

1

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

UN Number

3335

HS Code

2916 39 00