Product Identification

Product Name

2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride

Synonyms

Chlorethamine
Chlormethinum
Dichloren
Mustargen
N-Methylbis(2-chloroethyl)amine hydrochloride
Stickstofflost

CAS

55-86-7

Formula

C5H11Cl2N.ClH

Molecular Weight

192.52

EINECS

200-246-0

RTECS

IA2100000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data

Beilstein/Gmelin

605323

Beilstein Reference

4-04-00-00446

Physical and Chemical Properties

Appearance

White to off-white crystals or powder with a fishy odor.

Solubility in water

Soluble

Melting Point

-60

Boiling Point

87 (18 torr)

Density

1.118 g/cm3 (25 C)

Heat Of Vaporization

Usage

Prototype anticancer chemotherapeutic drug. Formerly used as a war gas.

Refractive Index

1.4689 (24 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Poison room locked.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Inhalation of vapors or dust is extremely irritating. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful.

Eyes

May cause burning of eyes and flow of tears.

Hazards

Containers may explode when heated.

UN (DOT)

1693

Exposure Controls/Personal Protection

Personal Protection

If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

The toxological properties of this substance have not been fully investigated.

Exposure limit(s)

OSHA: Possible Select carcinogen

Fire Fighting Measures

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - moisture.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1693

Hazard Class

6.1

Packing Group

II