Product Identification

Product Name

Caffeic acid

Synonyms

3-(3,4-Dihydroxyphenyl)-2-propenoic acid
3,4-Dihydroxybenzeneacrylic acid
3,4-Dihydroxycinnamic acid
4-(2-Carboxyethenyl)-1,2-dihydroxybenzene
4-(2'-Carboxyvinyl)-1,2-dihydroxybenzene

CAS

331-39-5

Formula

C9H8O4

Molecular Weight

180.16

EINECS

206-361-2

RTECS

GD8950000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Natural Product

Merck

13,1635

Beilstein/Gmelin

2210883

Beilstein Reference

2-10-00-00294

EC Class

carcinogenic

Physical and Chemical Properties

Appearance

Yellow prisms or plates (from chloroform or ligroin) or pale yellow granules. Alkaline solutions turn from yellow to orange.

Solubility in water

Very soluble

Melting Point

234 - 237

Boiling Point

366

pKa/pKb

4.04 (pKa)

Partition Coefficient

1.15

Usage

Inhibitor of poly(ethylene glycol) oxidation.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

The toxicological properties of this substance have not been fully investigated.

Skin

No information regarding skin irritation and other potential effects was found.

Eyes

May cause eye irritation. No information regarding eye irritation and other potential effects was found.

Ingestion

The toxicological properties of this substance have not been fully investigated.

EC Risk Phrase

R 36/37/38 40

EC Safety Phrase

S 22 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

The toxological properties of this substance have not been fully investigated.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Disposal Code

4

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong bases.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code

2918 29 90