Product Identification

Product Name

2-Nitroaniline

Synonyms

1-Amino-2-nitrobenzene
o-Nitroaniline

CAS

88-74-4

Formula

C6H6N2O2

Molecular Weight

138.13

EINECS

201-855-4

RTECS

BY6650000

RTECS Class

Mutagen

Merck

12,6680

Beilstein/Gmelin

509275

Beilstein Reference

4-12-00-01563

EC Index Number

612-012-00-9

EC Class

Toxic; Danger of cumulative effects; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Orange solid with a musty odor.

Solubility in water

1.1 g/L

Melting Point

68 - 71

Boiling Point

284

Vapor Pressure

0.003 (25 C)

Density

1.446 g/cm3 (20 C)

pKa/pKb

-0.26(at 25℃) (pKa)

Partition Coefficient

1.83

Heat Of Vaporization

52.4 kJ/mol

Heat Of Combustion

-3029 kJ/mol

Usage

Chemical intermediate for ci pigment yellow 5, orange 2, yellow 7, vat red 15, vat orange 7, ci pigment orange 43, vat red 14, disperse yellow 10.

Refractive Index

1.5362 (100 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Dust is irritating to the respiratory tract.

Skin

Causes skin irritation.

Eyes

Dust may cause mechanical irritation.

Ingestion

May be harmful if swallowed. Causes digestive tract irritation.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 23/24/25 33 52/53

EC Safety Phrase

S 28 36/37 45 61

UN (DOT)

1661

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review

Exposure limit(s)

NIOSH: Potential Occupational Carcinogen.

Fire Fighting Measures

Flash Point

126

Autoignition

521

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire, use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam.

Upper exp. limit

9.8

Lower exp. limit

1.5

Fire Potential

Slightly flammable. Flammable at elevated temperatures - moderate hazard.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Acids - acid chlorides - acid anhydrides - chloroformates - strong oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Toxic oxides of nitrogen may form in fire.

Transport Information

UN Number

1661

Hazard Class

6.1

Packing Group

II

HS Code

2921 42 10