Product Identification

Product Name

4-Methylnitrobenzene

Synonyms

1-Methyl-4-nitrobenzene
4-Hydroxynitrobenzene
4-Nitrotoluene
p-Methylnitrobenzene

CAS

99-99-0

Formula

C7H7NO2

Molecular Weight

137.13999999999999

EINECS

202-808-0

RTECS

XT3325000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector

Merck

12,6748

Beilstein/Gmelin

1906911

Beilstein Reference

4-05-00-00848

EC Index Number

609-006-00-3

EC Class

Toxic; Danger of cumulative effects; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Colorless to yellow solid with a weak aromatic odor.

Solubility in water

0.4 g/L

Melting Point

51

Boiling Point

238.3

Vapor Pressure

0.04 (20 C)

Density

1.299 g/cm3 (0 C)

Partition Coefficient

2.37

Heat Of Vaporization

50.2 kJ/mol

Heat Of Combustion

-4768 kJ/mol

Usage

Synthesis of intermediates & explosives.

Vapor Density

4.72

Saturation Concentration

132 ppm at 20 C

Refractive Index

1.53019 (55 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid prolonged or repeated contact with skin. Wash clothing before reuse.

Hazards Identification

Inhalation

Harmful if inhaled. Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation and possible burns.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May be harmful if swallowed.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 23/24/25 33 51/53

EC Safety Phrase

S 28 37 45 61

UN (DOT)

1664

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Effects may be delayed.

Exposure limit(s)

TLV (as TWA): 2 ppm; 11 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 5 ppm (30 mg/m3) skin NIOSH REL: TWA 2 ppm (11 mg/m3) skin NIOSH IDLH: 200 ppm

Poison Class

3

Fire Fighting Measures

Flash Point

106

Autoignition

456

Fire Fighting

Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Solid streams of water may be ineffective. Use foam, dry chemical, or carbon dioxide.

Upper exp. limit

7.6

Lower exp. limit

1.6

Fire Potential

Slightly flammable. Combustible.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition.

Stability and Reactivity

Disposal Code

9

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizing agents; Strong bases; Reducing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Yields toxic oxides of nitrogen when burning.

Transport Information

UN Number

1664

Hazard Class

6.1

Packing Group

II

HS Code

2904 20 00