Product Identification

Product Name

p-Aminophenylacetic acid

Synonyms

2-(4-Aminophenyl)acetic acid
4-(Carboxymethyl)aniline
4-Aminophenylacetic acid
p-Aminophenylacetic acid

CAS

1197-55-3

Formula

C8H9NO2

Molecular Weight

151.16999999999999

EINECS

214-828-7

RTECS

AF3550000

RTECS Class

Drug; Mutagen

Merck

13,462

Beilstein/Gmelin

2208094

Beilstein Reference

3-14-00-01182

Physical and Chemical Properties

Appearance

Light yellow to beige powder.

Solubility in water

Very soluble

Melting Point

199 - 202

Boiling Point

322

pKa/pKb

3.83 (pKa)

Partition Coefficient

.73

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema. Causes irritation of the mucous membrane and upper respiratory tract.

Skin

Causes skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

Causes eye irritation. The toxicological properties of this material have not been fully investigated. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures. Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

HS Code

2922 49 95