Product Identification

Product Name

2-Amino-3-[(2-amino-2-carboxyethyl)dithio]propanoic acid

Synonyms

(2R)-2-Amino-3-[(2R)-2-amino-3-hydroxy-3-oxopropyl]disulfanylpropanoic acid
L-(-)-3,3'-Dithiobis (2-aminopropionic acid)

CAS

56-89-3

Formula

C6H12N2O4S2

Molecular Weight

240.3

EINECS

200-296-3

RTECS

HA2690000

RTECS Class

Drug

Merck

13,2811

Beilstein/Gmelin

1728094

Beilstein Reference

4-04-00-03155

Physical and Chemical Properties

Appearance

White powder. A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.

Solubility in water

110 mg/L

Melting Point

261 - 262

Boiling Point

428

Density

1.677 g/cm3

pKa/pKb

1.0, 2.1, 8.02, 8.71(at 25℃) (pKa)

Partition Coefficient

-1.38

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Low hazard for usual industrial handling.

Inhalation

Low hazard for usual industrial handling.

Skin

Low hazard for usual industrial handling.

Eyes

Contact may cause transient eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Disposal Code

31

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizers.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.

Transport Information

HS Code

2930 90 14