Product Identification

Product Name

1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid

Synonyms

1-(2,4-Dichlorbenzyl)-indazole-3-carboxylic acid
1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid
AF-1890
DICA
Diclondazolic acid
Doridamina

CAS

50264-69-2

Formula

C15H10Cl2N2O2

Molecular Weight

321.16000000000003

EINECS

256-510-0

RTECS

NK7886000

RTECS Class

Drug; Mutagen; Reproductive Effector

Merck

12,5598

Beilstein/Gmelin

894483

Beilstein Reference

5-25-04-00250

Physical and Chemical Properties

Solubility in water

Slightly soluble

Melting Point

207 - 208

Boiling Point

538

Vapor Pressure

2E-12 (25 C)

pKa/pKb

3.47 (pKa)

Heat Of Vaporization

85.8 kJ/mol

Usage

Anti-neoplastic medication.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

60 22 40

EC Safety Phrase

53 22 36/37/39 45

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Toxic. May impair fertility. Harmful if swallowed. Limited evidence of a carcinogenic effect. Target organ(s): Ears. Testes.

Fire Fighting Measures

Flash Point

279

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.